产品货号：
Z38449
中文名称：
GRB7抗体
英文名称：
Anti-GRB7 Antibody (Clone#OTI6H2)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GRB7 Antibody (Clone#OTI6H2) |
| 指标别名 | B47;GRB7;GRB7 adapter protein |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | GRB7 |
| 克隆号 | OTI6H2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Full length human recombinant protein of human GRB7 (NP_005301) produced in E.coli. |
| 实际分子量 | 59.5KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | GRB7,growth factor receptor-bound protein 7,is a protein which in humans is encoded by the GRB7 gene.The product of this gene belongs to a small family of adaptor proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules.This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor(EGFR) and ephrin receptors.The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase(FAK).Alternative splicing results in multiple transcript variants encoding different isoforms,although the full-length natures of only two of the variants have been determined to date.GRB7 is an SH2-domain adaptor protein that binds to receptor tyrosine kinases and provides the intra-cellular direct link to the Ras proto-oncogene.Human GRB7 is located on the long arm of chromosome 17,next to the ERBB2(alias HER2/neu) proto-oncogene.These two genes are commonly co-amplified(present in excess copies) in breast cancers.GRB7 though to be involved in migration,is well known to be over-expressed in testicular germ cell tumors,esophageal cancers,and gastric cancers. |
| Uniprot ID | Q14451 |
| 基因名全称 | growth factor receptor bound protein 7 |
| 蛋白名全称 | Growth factor receptor-bound protein 7 |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:2000 |
相关搜索：GRB7抗体，GRB7单抗，Anti-GRB7 Antibody (Clone#OTI6H2)